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Comorbidities in Psoriasis. How Dangerous Can They Be?

In scenario were severe psoriasis emerges, there is an increased risk of serious comorbidities that are important to know and to prevent.

Early detection will allow to initiate the proper treatment for these diseases, preventing their progression to more severe forms is of utmost importance.

And in this regard, the primary care physician plays an essential role from a privileged position in detecting these comorbidities.

Comorbidities in Psoriasis. What Are They?

Psoriasis Comorbidities

Psoriasis comorbidities are worth paying attention to. Psoriasis is a systemic disease that involves more than skin lesions, internal organs can also be affected.

A comorbidity is quite common, psoriasis patients and their healthcare providers need to be aware of symptoms that may indicate other diseases.

They will need to be cautious with: cardiovascular problems, gastrointestinal problems, diabetes (type 2), and inflammatory eye diseases.

Recent evidence also suggests that psoriasis increases the likelihood of the phenomenon of restless legs.

What causes these associations have not yet been identified.

Psoriasis is a genetic disease, and it’s likely that certain genes determine who is at risk of developing any comorbidity.

Knowing that in advance would make possible to plan an effective and adequate treatment for one’s psoriasis and ultimately reduce the excessive inflammation in their body.

Metabolic Syndrome

When you have psoriasis there is a higher risk for developing metabolic syndrome. This umbrella term is used for describing the risk factors that increase the risk of cardiovascular diseases.

Among them are: abdominal obesity, type 2 diabetes, impaired blood lipids, increased cholesterol levels, and high blood pressure.

Psoriatic Arthritis and Joint Disorders

Psoriatic arthritis is the most common form of comorbidity and has been known for the longest time.

Many people living with psoriasis report joint pain, and studies suggest that up to 40% are diagnosed with psoriatic arthritis.

Type 2 Diabetes

Type 2 diabetes is twice as common in individuals with psoriasis, and particularly if you have a severe form of psoriasis.

Just by having type 2 diabetes already puts you at risk for other serious diseases.

Gastrointestinal Diseases

Due to scientific research we know now that there is a link between inflammatory bowel disease and psoriasis.

The diseases that belong to this group are Crohn’s disease and ulcerative colitis.

Cardiovascular Diseases

The risk for cardiovascular disease is higher in psoriasis patients than in healthy people. This link seems to be particularly true in severe psoriasis, because is where the risk is higher.

Young people with severe psoriasis appear to be at even greater risk. Some studies suggest that the risk could be as four times higher regarding to other patients.

Continuous research is being done in this area, and each passing year more discoveries are made.

Ophthalmic Diseases

Eye inflammation is common in psoriasis, so be sure to tell your doctor if you have problems with your eyes.

You may need to be referred to an ophthalmologist for assessment, and some adjustment may be done to your treatment plan.

High Blood Pressure

People with severe psoriasis have an increased risk of hypertension. It is more common in people with severe psoriasis than in healthy people.

This risk does not apply to newcomers or people with mild psoriasis.


Sadly, depression is also common in psoriasis, especially when the disease is widespread and very painful.

Psoriasis can significantly impact the quality of life, and many people end up being lonely and isolated by their illness.

Recent research also points to a link between inflammatory disease and depression. If you are feeling down or depressed, it is important to discuss this with your doctor.

Comorbidities in psoriasis is something to be taken seriously, contact your doctor if you suspect that you are being affected by other diseases.

Is Psoriasis a Comorbidity for COVID 19?

The Centers for Disease Control and Prevention (CDC) are not including people with psoriasis and other autoimmune diseases among those at risk.

But it is worth to mention that people with psoriasis may have additional comorbidities that will put them at risk for contracting COVID-19.

Should I Get the COVID Vaccine if I Have Psoriasis?

Yes, it is recommended to get COVID-19 vaccine. Only if your healthcare provider tells you otherwise then you shouldn’t take it.

People with psoriasis should be aware of other conditions that can increase their risk in case of a COVID-19 infection.

Is There a COVID-19 Vaccine for Immunocompromised Patients?

There isn’t a specific vaccine for immunocompromised patients.

The CDC and professional societies recommend SARS-CoV-2 vaccination for all the individuals, including the immunocompromised population.

Does Having Psoriasis Make You More Susceptible to COVID 19?

There is higher risk consequences if psoriasis patients end up contracting COVID-19 infection. A recent study showed that there is a 33% increased risk for death in psoriasis patients.

Does Having Psoriasis Make Your Immune System Weaker?

Having psoriasis doesn’t make your immune system weaker, but because it exists it is a sign that your immune system isn’t working as it should.

If anything attacks your immune system it will trigger psoriasis flare ups. Many simple ailments such as respiratory or ear infections can cause an psoriasis outbreak.

Is It Important to Know All the Comorbidities in Psoriasis in Order to Avoid Any Danger?

The most important thing is to be aware that comorbidities in psoriasis exist and which ones are you prone to.

If you are conscious of what can happen to you due to certain reasons, you will be aware to take more responsible decisions about your lifestyle.

The sooner you start being selective and committed to your objective, the better your quality of life will be.

You don’t need 100% expert in this particular subject, but you should be very conscious about the choices you are making with your psoriasis.

Whatever you do will impact you for the rest of your life, start making healthy choices and don’t let psoriasis take away anything that you are untitled to.


Evidence increasingly suggests that there is a link between psoriasis and several comorbidities.

Therefore long-term control of the disease can improve positively the patients quality of life.

Early treatment of severe psoriasis and associated comorbidities can influence the well-being and probably the longevity of many psoriasis patients.